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Similarly, low levels of TS-miR-29c in HCC target tumor necrosis factor alpha-induced protein 3 to prevent apoptosis . Alteration of signaling pathways Tumor suppressor PTEN, a negative regulator of PI3K/AKT signaling is frequently targeted by elevated levels of miR-21, miR-222, and miR-29a in HCC ( 59, 64 ). miR-199-3p targets mTOR and c-Met, a HGF receptor, which controls downstream PAK4 ...
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Flavonol and flavone glycosides occur in common vegetables, mainly as the quercetin or kaempferol glycosides and less frequently as the luteolin or apigenin glycosides. Their formation normally depends on light, so they are mainly concentrated in the outer tissues. Their concentration in free-standing leaves is considerably greater than that in any other part of the same plant, with the ...
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Similarly, low levels of TS-miR-29c in HCC target tumor necrosis factor alpha-induced protein 3 to prevent apoptosis . Alteration of signaling pathways Tumor suppressor PTEN, a negative regulator of PI3K/AKT signaling is frequently targeted by elevated levels of miR-21, miR-222, and miR-29a in HCC ( 59, 64 ). miR-199-3p targets mTOR and c-Met, a HGF receptor, which controls downstream PAK4 ...
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With 59 in hand, we initially ... the mixture was warmed to 60 °C. [c] In this case the aziridinium was formed using Ag(BF 4). [d] In this case the N‐chloroamine was purified before addition of NaI.* Denotes the minor constitutional isomer. Having validated the conversion of the β‐chloroamine 11 into the corresponding aziridinium ion 59 and subsequent nucleophilic ring‐opening with a ...
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Recent reports showed KDM5B could interact with the transcription factors BF-1 and PAX9 and ... [59,,, ]. 3.2. KDM5B in cancer 3.2.1. KDM5B and breast cancer . KDM5B plays an important role in the progression of breast cancer, which is associated with transcription repression [64,65]. Overexpression of KDM5B was found in breast cancer cells, such as ER + MCF-7 cell. The expression of KDM5B ...
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With 59 in hand, we initially ... the mixture was warmed to 60 °C. [c] In this case the aziridinium was formed using Ag(BF 4). [d] In this case the N‐chloroamine was purified before addition of NaI.* Denotes the minor constitutional isomer. Having validated the conversion of the β‐chloroamine 11 into the corresponding aziridinium ion 59 and subsequent nucleophilic ring‐opening with a ...
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Recent reports showed KDM5B could interact with the transcription factors BF-1 and PAX9 and ... [59,,, ]. 3.2. KDM5B in cancer 3.2.1. KDM5B and breast cancer . KDM5B plays an important role in the progression of breast cancer, which is associated with transcription repression [64,65]. Overexpression of KDM5B was found in breast cancer cells, such as ER + MCF-7 cell. The expression of KDM5B ...
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